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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of choroidal neovascularization (CNV)
ncRNA name VEGF shRNA
ncRNA Category shRNA
Disease name choroidal neovascularization (CNV)
Species Homo sapiens
Tissues/Cell_line human RPE cell line ARPE-19
Methods transfection, luciferase reporter assay, RT-PCR
Expression pattern associated
Functional description Plasmids encoding anti-VEGF shRNAs showed efficient knockdown of human VEGF in RPEs.
PubMed ID 23080553
Year 2012
Title Reduction of choroidal neovascularization in mice by adeno-associated virus-delivered anti-vascular endothelial growth factor short hairpin RNA.
Drug-related ncRNA NA

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